AST plates manually interpreted; EUCAST v16.0 changes break legacy templates
12-25 min/plate, error rate 4-7% on legacy LIS
EUCAST v16.0 + CLSI M100-S34 breakpoint engine auto-interprets MIC and disk diffusion in <100 ms
AssayCore Micro is purpose-built for clinical and environmental microbiology laboratories. The system manages the full culture workflow from sample registration to final identification and antibiotic susceptibility reporting. Full EUCAST v16.0 and CLSI M100 (Ed35, 2025) breakpoint tables enable automated S/I/R interpretation. Expert rules engine detects ESBL, AmpC, CRE/Carbapenemase, MRSA, VRE, and intrinsic resistance phenotypes. Colony counter ML integration, incubation scheduling, and FHIR R4 antibiogram export complete the solution.
Compliance & Standards
Complete feature set covering every stage of your laboratory workflow.
Concrete laboratory pain — quantified — and how AssayCore Micro addresses each.
EUCAST v16.0 + CLSI M100-S34 breakpoint engine auto-interprets MIC and disk diffusion in <100 ms
EUCAST Expert Rules engine applies 60+ rules incl. methicillin-R → all β-lactams = R
ML colony counter (YOLOv8-based) reads plate photos in 2-3 s with confidence score
Auto-generated CLSI M39 antibiogram with infection-control trend overlay
Built-in environmental monitoring module mapped to ISO 14698 + EU GMP Annex 1 (2022)
ISO 4833 / 6579 / 11731 calculators baked into result-entry forms
Bundled CPU-only inference. Open datasets, transparent metrics, lab-tunable thresholds.
| Model | Task | Dataset | Metric | Latency | Status |
|---|---|---|---|---|---|
| micro.ast_predictor | Predict S/I/R for organism × antibiotic before final AST | Synthetic clinically-informed (HF: assaycore/micro-ast, EUCAST patterns) | Accuracy 0.89 | 12 ms (CPU) | Production |
| micro.mic_regressor | Predict MIC value (log2) for empiric dosing | Synthetic clinically-informed | MAE ~1 dilution (log2) | 15 ms (CPU) | Production |
| micro.phenotype_predictor | Predict phenotypic traits (motility, biofilm, hemolysis) | Synthetic + curated phenotype features | F1 0.83 multi-label | 18 ms (CPU) | Production |
| micro.organism_ner | Recognize organism mentions in clinical text | EMBO SourceData patterns (CC-BY 4.0, 338 patterns) | F1 0.92 | 10 ms (CPU) | Production |
| micro.microbiology_qa | Retrieval QA over microbiology corpus | Curated 36-doc microbiology seed corpus | Recall@5 0.78 | 55 ms (CPU) | Production |
| micro.colony_counter | Count colonies on plate photos and segment morphotypes | AGAR (HF: assaycore/agar-colonies, 18K labelled images) | MAE 3.2 colonies / image | GPU only (320 ms CPU fallback) | GPU-only |
| micro.zone_measurement | Measure disk-diffusion zone diameter from image | Internal disk-diffusion image set (synthetic + real) | MAE 0.6 mm | GPU only | GPU-only |
Calculations that actually run in AssayCore Micro — every formula links to its source standard.
S if MIC ≤ S_breakpoint; R if MIC > R_breakpoint; I otherwiseEUCAST v16.0 (2024)
if Methicillin-R(S. aureus) → all β-lactams = R (except ceftaroline / ceftobiprole)EUCAST Expert Rules v3.2
S if zone ≥ S_diam; R if zone ≤ R_diam; I otherwiseCLSI M100-S34; CLSI M02-A13
CFU/g = (Σ colonies) / (n × V × dilution)ISO 4833-1:2013
%S = (n_S / n_total_isolates) × 100CLSI M39-A4
result = positive if (pre-enrichment + selective enrichment + biochemical + serological) all confirmISO 6579-1:2017
CFU/L = colonies × dilution / V_filtered (water)ISO 11731:2017
Honest side-by-side. Where competitors lead we say so; where we lead, we show how.
| Competitor | Their offer | AssayCore Micro |
|---|---|---|
| BD EpiCenter | Strong instrument integration but EpiCenter is BD-only ecosystem | Vendor-neutral HL7v2 + FHIR R4; works with BD, bioMérieux, Beckman, Bruker |
| bioMérieux MYLA / Vitek | Tied to Vitek instruments; weak open-format antibiogram export | FHIR R4 antibiogram + CLSI M39 cumulative report exports for any HIS |
| Roche cobas IT (microbiology) | Roche-locked, expensive, weak environmental monitoring module | Native EU GMP Annex 1 environmental monitoring + ISO 14698 hygiene workflow |
| TheraDoc / Sentri7 (Wolters Kluwer) | Surveillance dashboards but no AST automation | Full EUCAST v16.0 + CLSI M100-S34 AST + Expert Rules engine |
| STARLIMS Microbiology | Mature LIS but ML colony counter only via paid add-on | ML colony counter, organism NER, AST predictor included in starter SKU |
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